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CSC-Tübingen PhD Program: Project 05/2020:
Identification and Imaging of Extracellular Matrix (ECM) in Pathological Tissues
Topic Description:The aim of this project is to characterize human pathological and normal tissues. The student will employ 3D in vitro tissue models and patient-derived tissues to identify prevalent ECM components and to characterize the correlation between cell phenotypes and their microenvironment. Classical histochemical and biochemical assays will be employed to study ECM-composition and to identify glycosaminoglycans prevalent in pathological (e.g. fibrotic tissues, benign and malignant tumor tissues etc.) and control tissues. Advanced imaging techniques (Raman and Multiphoton Imaging) will be used to monitor production and deposition of ECM in the cell-specific microenvironment. Response of pathological and control cells (cell proliferation, migration, metabolism) and on different ECM components and GAGs will be investigated in a systematic manner. In vitro tissue models will be established to mimic pathological and normal tissues. Dynamic cellular processes (cell death, differentiation, proliferation) will be detected within the tissue models in a time-resolved manner using advanced imaging techniques.
Faculty: Faculty of Medicine
Institute/Section/Subject:Research Institute for Women’s Health / Regenerative Medicine
Supervising Professors:Prof. Schenke-Layland
About the Supervisors:Prof. Dr. Katja Schenke-Layland is the University Professor for Regenerative Medicine at the Eberhard-Karls-University Tübingen and the director of the Natural and Medical Science Institute (NMI) at the University of Tübingen. Our research focusses on cell/stem cell and extracellular matrix biology, tissue engineering and biomaterials design. For these applications we employ advanced microscopic imaging techniques such as Raman and multiphoton imaging for the label-independent evaluation of native and engineered tissues and for the monitoring of cell and tissue responses in vitro. The PhD student will be directly supervised by Dr. Eva Brauchle, a junior group leader in the team of Prof. Schenke-Layland.
More information: www.schenke-layland-lab.com
Requirements for the application:Required Degrees: Master of Sciences or Engineering (Biology, Biomedical Engineering or related)
Language Requirements: English
Notes: Experience in microscopy, cell culture and/or image analysis is a plus
For further instructions on how to apply, more information on the program and contact details please see below.
CSC-Tübingen PhD Program
The China Scholarship Council (CSC) and the University of Tübingen have established a PhD Program which supports Chinese nationals inside and outside of China wishing to carry out all or part of their PhD study in Tübingen.
- providing high quality research training to qualified students from Chinese universities
- developing education and research collaborations between the University of Tübingen and Chinese universities and research institutions
Excellent postgraduate and doctoral students from Chinese universities who are citizens and permanent residents of the People’s Republic of China at the time of application
Details: Full time fellowship:
- postgraduate students who want to carry out their complete doctoral studies at the University of Tübingen
- up to 48 months
- degree conferred by the University of Tübingen
- Annual living allowance as prescribed by the Chinese Government (which includes Overseas Student Health Cover)
- Return airfare to Germany
- Visa application fees
- Support for the attendance of international conferences during the second and third year (up to 1000€ granted to successful applicants)
- Tuition waiver
- Option to take German language classes provided by the University of Tübingen during the first year
- Accommodation offered in Tübingen student dormitories depending on availability
- Opportunities to gain additional teaching and research experience as well as economic benefits from the University of Tübingen from the second year onward (depending on the ability of the applicant and the situation of the respective institute)
- Jan 15: Application deadline. Applications must be handed in through the online application system of the University of Tübingen
- by March 1: Successful applicants will be officially informed
- by April 5: Invited applicants have to register with the CSC according to the regulations of the CSC.
- by May 31: Final decisions about the allocation of scholarships will be made by the CSC
- June: Program participants will be invited for a welcome seminar in Beijing
- by Oct 1: Program participants arrive in Tübingen
- Successful candidates must return to China upon completion of their studies.
How to Apply:
In order to apply you need to upload the following documents combined in 1 PDF
- Cover/Motivation letter
- Research proposal
- Academic transcripts
- Proof of proficient skills in the required languages (if possible certificates, proficiency=comprehension of a wide range of demanding, longer texts as well as fluent and spontaneous expression allowing a flexible and effective language use for social, academic and professional purposes.)
For questions please contact the representation of the University of Tübingen in Beijing:
European Centre for Chinese Studies (ECCS)
Mr. Christian Buskühl
Peking University Pacific Science and Technology Development Center
52, Haidian Road, Haidian District, Beijing 100080 / Room 708
北京大学太平洋科技发展中心, 北京市 海淀区 海淀路52号 708室 / 邮编: 100080